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When the chemistry is no longer there.
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When your partner's flaw's start glaring
out at you like giant cracks in a mirror
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When you suddenly realize that your
personalities are mismatched or clash with each other.
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When both of you start fighting / arguing
over petty issues.
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When you do not see eye to eye and little
things start irritating you.
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When you or your partner starts avoiding
the other
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When your interests start diverging to
opposite extremes.
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When either of you start looking for
excuses to not be together.
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When either of you start lying and
keeping secrets from each other.
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When you start keeping track of your
individual finances and expenditures.
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When you or your partner start making or
receiving hurried secret phone calls ... ie either of you start
cheating.
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When either of you starts abusing the
other emotionally or physically.
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When guilt, jealousy, anger or hatred take
over.
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When you start feeling relaxed away from
the other.
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When being together feels like a big
burden.
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When you simply hate the guts / sight /
physical behaviors of the other
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When your 'intuition' or heart tells you
so.
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When you know that it will simply not work
any longer.